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Companion Animals Therapeutic Monitoring
Therapeutic Drug Monitoring
Phenobarbitone [PBAR]
Serum (clotted blood) or heparin plasma (not serum gel tubes).
Sample 12 hours post tablet, 2-3 weeks after commencing treatment or adjusting dosage, then every 6 - 12 months.

Phenobarbitone & potassium bromide [PBAR KBR]
Serum (clotted blood) or heparin plasma (not serum gel tubes).
Sample 12 hours post tablet, 2-3 weeks after commencing treatment or adjusting dosage, then every 6 - 12 months.

Potassium Bromide [KBR]
Serum (clotted blood) or heparin plasma (not serum gel tubes).
Sample 125 days after commencing treatment or adjusting dosage, then every 6-12 months.

Phenytoin [PHEN]
Serum (clotted blood)

Digoxin [DIG]
Serum (clotted blood) or heparin plasma (not serum gel tubes).
Sample 8 hours post tablet, 5 days after commencing treatment or adjusting dosage, or if signs suspicious of toxicity becomes apparent.

Thyroxine Therapy - T4 [T4]
Serum (clotted blood) or heparin plasma.
Sample 4-6 hours post tablet.

Carbimazole / Methimazole Therapy - T4 [T4]
Serum (clotted blood) or heparin plasma.
Sample 1 - 3 weeks after commencing treatment, 2 weeks after each dose adjustment, then every 3 months.

Trilostane Therapy - ACTH Stimulation Test [CORT* x2]
Serum (clotted blood) or heparin plasma x2.
Take first sample 4 - 6 hours post tablet. Inject 0.25 mg synthetic ACTH (Synacthen) I/v or I/m, then resample 1 hour later. Label samples clearly pre and post ACTH. Test 10 days, 4 weeks, 12 weeks and every 3 months after initial treatment or following disease.

Disease Monitoring & Diagnosis
Fructosamine [FRUC]
Serum (clotted blood) or heparin plasma.
Monitor glycaemic control.
More details

Diabetic Monitoring [DMON]
Serum (clotted blood) or heparin plasma and oxalate fluoride blood.
Fructosamine and glucose concentrations.
More details

Troponin I [TROP]
Serum (clotted blood) or heparin plasma.
Indicator of acute (48hr) mycocardinal infarction in canines (and equines). Also useful biomarker for acquired canine cardiac disease.

Anti acetylcholine receptor antibody test [Anti ACHab]
Serum (clotted blood) only.
Diagnosis of myasthenia gravis

2m Antibody test [2m AB]
Serum (clotted blood) only.
Diagnosis of canine masticatory myositis

Pancreatic lipase immunoreactivity [PLI]
Serum (clotted blood) only.
Diagnosis of pancreatitis, canine and feline.