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Companion Animals Therapeutic Monitoring
Therapeutic Drug Monitoring Phenobarbitone [PBAR] Serum (clotted blood) or heparin plasma (not serum gel tubes).Sample 12 hours post tablet, 2-3 weeks after commencing treatment or adjusting dosage, then every 6 - 12 months. Phenobarbitone & potassium bromide [PBAR KBR] Serum (clotted blood) or heparin plasma (not serum gel tubes).Sample 12 hours post tablet, 2-3 weeks after commencing treatment or adjusting dosage, then every 6 - 12 months. Potassium Bromide [KBR] Serum (clotted blood) or heparin plasma (not serum gel tubes).Sample 125 days after commencing treatment or adjusting dosage, then every 6-12 months. Phenytoin [PHEN] Serum (clotted blood)
Digoxin [DIG] Serum (clotted blood) or heparin plasma (not serum gel tubes).Sample 8 hours post tablet, 5 days after commencing treatment or adjusting dosage, or if signs suspicious of toxicity becomes apparent. Thyroxine Therapy - T4 [T4] Serum (clotted blood) or heparin plasma.Sample 4-6 hours post tablet. Carbimazole / Methimazole Therapy - T4 [T4] Serum (clotted blood) or heparin plasma. Sample 1 - 3 weeks after commencing treatment, 2 weeks after each dose adjustment, then every 3 months. Trilostane Therapy - ACTH Stimulation Test [CORT* x2] Serum (clotted blood) or heparin plasma x2. Take first sample 4 - 6 hours post tablet. Inject 0.25 mg synthetic ACTH (Synacthen) I/v or I/m, then resample 1 hour later. Label samples clearly pre and post ACTH. Test 10 days, 4 weeks, 12 weeks and every 3 months after initial treatment or following disease. Disease Monitoring & Diagnosis Fructosamine [FRUC] Serum (clotted blood) or heparin plasma.Monitor glycaemic control. More details Diabetic Monitoring [DMON] Serum (clotted blood) or heparin plasma and oxalate fluoride blood.Fructosamine and glucose concentrations. More details Troponin I [TROP] Serum (clotted blood) or heparin plasma.Indicator of acute (48hr) mycocardinal infarction in canines (and equines). Also useful biomarker for acquired canine cardiac disease. Anti acetylcholine receptor antibody test [Anti ACHab] Serum (clotted blood) only.Diagnosis of myasthenia gravis 2m Antibody test [2m AB] Serum (clotted blood) only.Diagnosis of canine masticatory myositis Pancreatic lipase immunoreactivity [PLI] Serum (clotted blood) only.Diagnosis of pancreatitis, canine and feline. |
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